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differential arthritis hematology oncology classification erythematosus leukemia sle systemic vasculitis chronic cll disease hodgkins laboratory lymphoma management monoarthritis monoarticular oligoarthritis
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint ... Pain - Diagnostic ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Approach to Joint ... or nerve root Symptoms ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... lesions Abdominal pain ... ) Blood (75%): Anemia ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... • Neutropenia, anemia ... Pure red cell aplasia ... #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
infections, bone pain ... , fever, joint pain ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Approach to Joint ... Differential Diagnosis ... constitutional symptoms ... #Diagnosis #MSK ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
tract: Abdominal pain ... • Progressive symptoms ... elevated protein, lymphocytic ... Palpable purpura, joint ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Arthritis: • Joint ... pain • Swan neck ... lymphopenia, low PLT • Anemia ... : • Symptoms limited ... #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... • Pain in LN ... ingestion • B symptoms ... Hodgkin Lymphoma Workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... • Systemic lupus ... the presence of anemia ... , and low back pain ... #Rheumatology
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