9 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... • Systemic Lupus ... Age > 50 • Chronic ... Lymphocytes) - Monoclonal ... #Oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Can Feature A Monoclonal ... Amyloidosis and monoclonal ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... • Immunologic Workup ... • Evolution: Chronic ... comparison #table #rheumatology ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... minimal tumor burden Diagnosis ... fludarabine) 3) Monoclonal ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
to Joint Pain - Diagnostic ... spondyloarthropathies, lupus ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... phenomenon CLL Diagnosis ... #workup #oncology ... #hematology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
or nerve root Symptoms ... : • Acute or chronic ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
rapidly progressing GN ... Eosinophilia, asthma, chronic ... such as systemic lupus ... Presentation - Systemic Symptoms ... #rheumatology #
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... Marrow Failure • Chronic ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology