5 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... • Limited to Kidney ... #diagnosis #algorithm ... #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
) - Loss of kidney ... IgA nephropathy, lupus ... post-infectious GN ... Classification #Differential ... #Diagnosis #Nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... (AKI) - Differential ... Vasculitis • GN ... Med, Contrast, Pigment ... #causes #algorithm
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Drug Induced Kidney ... FSGS, Membranous GN ... @kdjhaveri #DrugInduced ... #KidneyInjury #differential ... #diagnosis #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
rapidly progressing GN ... inflammation Others: • Lupus ... such as systemic lupus ... Kidneys -> glomerulonephritis ... #diagnosis #rheumatology