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diagnosis nephrology classification glomerulonephritis vasculitis acute aki causes druginduced erythematosus injury kidneyinjury progressive rapidly sle systemic vasculitides
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... • Limited to Kidney ... #diagnosis #algorithm ... #rheumatology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... (AKI) - Differential ... Vasculitis • GN ... Med, Contrast, Pigment ... nephrology #causes #algorithm
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
) - Loss of kidney ... of glomerular disease ... IgA nephropathy, lupus ... post-infectious GN ... Classification #Differential
Drug Induced Kidney Injury • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy • Osmotic
Drug Induced Kidney ... • Glomerular Disease ... FSGS, Membranous GN ... #diagnosis #algorithm ... #nephrology #Medications
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... C4) • ds-DNA: Kidney ... induced SLE • Kidney ... activation and/or medications
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... inflammation Others: • Lupus ... such as systemic lupus ... Kidneys -> glomerulonephritis ... #diagnosis #rheumatology
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