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diagnosis nephrology classification glomerulonephritis acute aki causes druginduced erythematosus hematology injury kidneyinjury medications monoclonal oncology paraproteinemias progressive rapidly sle systemic
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... • Limited to Kidney ... #differential # ... #rheumatology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... Emboli, Thrombosis, Vasculitis ... • GN: ANCA, Anti-GBM ... Med, Contrast, Pigment ... nephrology #causes #algorithm
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
) - Loss of kidney ... of glomerular disease ... IgA nephropathy, lupus ... post-infectious GN ... Classification #Differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... rapidly progressing GN ... inflammation Others: • Lupus ... such as systemic lupus ... #rheumatology #
Drug Induced Kidney Injury • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy • Osmotic
Drug Induced Kidney ... • Glomerular Disease ... : Drug induced vasculitis ... FSGS, Membranous GN ... #diagnosis #algorithm
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... musculoskeletal systems • Kidneys ... #Differential #Diagnosis ... #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Autoimmunity: • -MM/WM: Vasculitis ... to cold IgG • Lupus ... Sneddon-Wilkinson disease ... #Monoclonal #Differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... C4) • ds-DNA: Kidney ... induced SLE • Kidney ... Erythematosus #Diagnosis #Rheumatology
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