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diagnosis differential sle vasculitis antiphospholipid classification comparison druginduced glomerulonephritis hematology hypercoagulable management progressive rapidly rpgn syndrome systemic table vasculitides
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Antiribosomal P, APLA ... C4) • ds-DNA: Kidney ... induced SLE • Kidney ... #Diagnosis #Rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... • Limited to Kidney ... differential #diagnosis #algorithm ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
myalgia, serositis, Kidney ... • Immunologic Workup ... Erythematosus ( ... • Immunologic Workup ... comparison #table #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... inflammation Others: • Lupus ... such as systemic lupus ... erythematosus, ... differential #diagnosis #rheumatology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid Syndrome (APLS ... Hypercoagulable Workup ... Algorithm INDICATIONS ... excluded Testing: • Lupus ... #hematology
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