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diagnosis differential antiphospholipid causes classification dermatology erythematosus glomerulonephritis hypercoagulable petechiae petechial physicalexam progressive rapidly rash rpgn sle syndrome systemic vasculitides
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... • Limited to Kidney ... Glomerulonephritis #Vasculitis ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... vein thrombosis Hematologic ... C4) • ds-DNA: Kidney ... induced SLE • Kidney ... Erythematosus #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... inflammation Others: • Lupus ... such as systemic lupus ... Kidneys -> glomerulonephritis ... differential #diagnosis #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Infection - Vasculitis ... (lupus, RA, Sjogren's ... Rash: - ITP - APLS ... deficiency Work
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid Syndrome (APLS ... Hypercoagulable Workup ... Algorithm INDICATIONS ... excluded Testing: • Lupus ... #hematology
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