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diagnosis hematology differential activation altered anemia aplastic cerebritis encephalopathy erythematosus hypertension leukemia macrophage monoclonal neurology paraproteinemias sle syndrome systemic treatment
Hypertension and Altered Mental Status (AMS) - Differential Diagnosis Framework Hypertension: • Hypertensive emergency • Hypertensive encephalopathy
Mental Status (AMS ... • Intracranial mass ... Renal: • Acute GN ... Vasculitis • Lupus ... #Hypertension #AMS
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
myopathy • Anti MAG ... Scleromyxedema (CNS ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... autoantibodies that will cause ... (for secondary APS ... #neurology #rheumatology ... cerebritis #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Activation Syndrome (MAS ... cytokines, such as ... manifestation of MAS ... nervous system (CNS ... Plasma exchange #MAS
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as ... pts with GCA or as ... chorioretinitis, CNS ... and episcleritis as ... well as inner ear
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL can present as ... ALL: mediastinal mass ... involvement • 30%: CNS ... : Blast crises ... #Oncology #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... to repair DNA, as ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
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