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diagnosis sle algorithm erythematosus signs symptoms systemic table vasculitis autoimmune classification dermatology druginduced glomerulonephritis hematology management mimickers monoclonal myopathy myositis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Complement: Post-strep GN ... , Lupus Nephritis ... Purpura Anti-GBM antibodies ... diagnosis #algorithm #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
SLE-Related Auto-Antibodies ... (aPL) 30-45% Differential ... Erythematosus #Diagnosis #autoantibodies ... symptoms #mimickers #differential ... #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
-C3 GN • Cast ... macular Vasculitis) Autoantibodies ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
cases, drug-dependent ... Discontinuation of causal ... months) and of autoantibodies ... #sle #comparison ... #table #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... Autoimmune Vasculitis (lupus ... of antinuclear antibodies ... #dermatology #physicalexam
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Anti-Ro/SSA autoantibodies ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... 1, SCL-70, RNP antibodies ... anticardiolipin antibodies
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
Features That Differentiate ... associated with rheumatologic ... presentation of systemic lupus ... life-threatening causes ... #Presentation #comparison
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 Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... tract, and often causes ... such as systemic lupus ... C-ANCA) pattern: antibodies ... #diagnosis #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... RP-ILD), dermato-rheumatologic ... Mechanic's hands Autoantibodies ... statins - probably caused ... #differential #
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