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diagnosis algorithm ana antinuclear arthritis causes erythematosus systemic vasculitis approach autoantibodies classification dermatology disease disorders glomerulonephritis hematology joint laboratory management
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... #Antinuclear #Antibodies ... #ANA #patterns ... #rheumatology #diagnosis ... #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... #Antinuclear #Antibodies ... #rheumatology #diagnosis ... #differential
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... Purpura Anti-GBM antibodies ... Glomerulonephritis #Vasculitis #differential ... diagnosis #algorithm #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
involvement 3% SLE-Related ... Auto-Antibodies ... (aPL) 30-45% Differential ... Lupusreference #SLE ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... 1, SCL-70, RNP antibodies ... anticardiolipin antibodies
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... test, ANA (e.g., SLE ... anti-phospholipid antibodies ... #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Autoimmune Vasculitis (lupus ... deficiency Work ... of antinuclear antibodies ... #dermatology #physicalexam
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... such as systemic lupus ... : antibodies directed ... vasculitis, and SLE ... #diagnosis #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... double-stranded DNA antibodies ... Arthritis #laboratory #workup ... diagnosis #testing #Rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
mononeuritis multiplex WORKUP ... EGPA) • Auto-antibodies ... • IF staining patterns ... in crescentic GN ... Renal #Syndromes #differential
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