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diagnosis differential vasculitis allergy erythematosus hypersensitivity reactions rpgn sle syndrome systemic table algorithm arthritis champs comparison complement cryoglobulinemia cryoglobulins disease
Renal Involvement in Systemic Lupus Erythematosus Dr. Laurent ARNAUD @Lupusreference #Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Lupusreference #Renal #diseases ... SLE #Systemic #Lupus ... Erythematosus #venn #nephrology ... #nephritis #classification ... #types #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
of glomerular disease ... IgA nephropathy, lupus ... post-infectious GN ... autoAb against type ... #RPGN #Classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Rapidly Progressive Glomerulonephritis ... Complement: Post-strep GN ... , Lupus Nephritis ... involvement: Anti-GBM Disease ... diagnosis #algorithm #rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Chain deposition disease ... , type 1 (50%-80% ... S - Systemic Lupus ... Ann Marie Kumfer ... #differential #hematology
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
binds to the lgE, cross-linking ... during hemolytic disease ... Post-streptococcal glomerulonephritis ... systemic lupus ... #Classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... Others: • Lupus ... such as systemic lupus ... differential #diagnosis #rheumatology ... #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Skin ulcers - Glomerulonephritis ... • Autoimmune diseases ... (e.g. systemic lupus ... #classification ... #rheumatology #
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of types ... reaction, Haemolytic disease ... Post-streptococcal glomerulonephritis ... , Systemic lupus ... allergy #table #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... Non-autoimmune rheumatologic ... • Type-I Interferonopathies ... Erythematosus #Diagnosis #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
IV RTA, TYPE I ... nephritis • Distal (Type ... acidosis • NAGMA • Glomerulonephritis ... Membranoproliferative GN ... Sjogrens #Syndrome #Rheumatology
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