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diagnosis erythematosus hypersensitivity pathophysiology reactions systemic table vasculitis comparison criteria cryoglobulinemia cryoglobulins differential disease eularacr hypersensitivityreaction immunology laboratory management rheumatic
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
Type III Hypersensitivity ... : • Systemic Lupus ... Erythematosus (SLE ... the cause: • Arthritis ... HypersensitivityReaction #Allergy
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
When the specific allergen ... Type Ill - IgG and ... glomerulonephritis, rheumatoid arthritis ... , and systemic lupus ... #Classification
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... • Arthritis domain ... low C4, Low C3 and ... #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... Examples: Rheumatoid arthritis ... glomerulonephritis, Systemic lupus ... #allergy #table ... #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... Skin Disease Classification ... Non-autoimmune rheumatologic ... Kikuchi disease • Type-I
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
arthritis) • ... Types II and III ... (e.g. systemic lupus ... #classification ... #rheumatology #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Diseases • Septic arthritis ... joint • Systemic lupus ... Tests for All Types ... diagnosis #testing #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... LFT • ESR • ANA ... SLE) • Urinalysis ... differential #diagnosis #rheumatology ... #classification
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... IV RTA, TYPE I ... Membranoproliferative GN ... Arthritis Malignancy ... Sjogrens #Syndrome #Rheumatology
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