9 results
Approach to managing Glomerulonephritis (GN) in children. 

ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
(GN) in children ... cytoplasmic antibodies; SLE ... , systemic lupus ... erythematosus. ... #Glomerulonephritis
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
: • Systemic Lupus ... • Erythematosus ... (SLE) If bacterial ... Post-infectious glomerulonephritis ... HypersensitivityReaction #Allergy
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Erythematosus ... low C4, Low C3 and ... #Criteria #SLE ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... Skin Disease Classification ... Non-autoimmune rheumatologic ... #Diagnosis #Rheumatology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... Post-streptococcal glomerulonephritis ... systemic lupus ... erythematosus Type ... Hypersensitivity #Types #Classification
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
rapidly progressing GN ... erythematosus, ... SLE) • Urinalysis ... differential #diagnosis #rheumatology ... #classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Post-streptococcal glomerulonephritis ... , Systemic lupus ... erythematosus Type ... reactions #types #allergy ... #table #classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Skin ulcers - Glomerulonephritis ... (e.g. systemic lupus ... erythematosus ( ... diagnosis #types #classification ... #rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... ischemia • Skin: Erythematous ... , pauci-immune glomerulonephritis ... Mononeuropathy, Glomerulonephritis ... Differential #Diagnosis #Rheumatology