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diagnosis differential hematology management vasculitis classification dermatologic erythematosus gpa granulomatosis macrophage oncology polyangiitis rash sapho sle sweet systemic tryptase vasculitides
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Syndrome (MAS) ... • Fever is the main ... #Management #Hematology ... #Rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Inflammation and pain ... Causes: - Idiopathic ... - Allergic contact ... - Lupus - Leukemia ... #diagnosis #dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Joint pain • Swan ... erythematosus (NPSLE): • May ... Chronic B-cell activation ... Erythematosus #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
tract: Abdominal pain ... tract, and often causes ... involvement, abdominal pain ... vasculitis • Cogan syndrome ... Differential #Diagnosis #Rheumatology
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
pass = Primary Causes ... : • Mast cell ... activation syndrome ... Differential #Diagnosis #hematology ... #allergy
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... burning sensation or pain ... • Goodpasture syndrome ... • Giant cell arteritis ... rash #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... tract, and often causes ... inflammation Others: • Lupus ... systemic lupus ... differential #diagnosis #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
nonerosive inflammatory arthritis ... thickening • Osteitis: pain ... Rule out other causes ... #Rheumatology # ... diagnosis #management #Dermatology
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