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diagnosis differential hematology management symptoms syndrome vasculitis classification joint algorithm mnemonic msk oncology rash activation anemia antibodies antimda5 antimda5dm antinuclear
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Autoimmune → Inflammation ... noninflammatory Signs ... weeks) Can Be Caused ... Rheumatologic Disease ... Diagnosis #MSK #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... Positive ANA ≠ Autoimmune ... Juvenile Idiopathic Arthritis ... Thyroid, Autoimmune ... #patterns #rheumatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Inflammatory and ... Autoimmune Diseases ... : • Systemic lupus ... • Epstein-Barr virus ... Differential #Diagnosis #Hematology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Causes of Isolated ... • Epstein-Barr Virus ... Destruction • Systemic Lupus ... • Rheumatoid Arthritis ... #Hematology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
GCA), Takayasu's arteritis ... Polyarteritis Nodosa (PAN ... ), ANCA associated ... (RA), Systemic lupus ... Differential #Diagnosis #rheumatology
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
- Loin pain hematuria ... syndrome: • Flank pain ... hematuria • Signs ... Diagnostic of GN ... Hematuria: • Urethritis
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Atypical HUS, autoimmune ... S - Systemic Lupus ... Ann Marie Kumfer ... #differential #hematology
MIAMI Mnemonic for Differential Diagnosis of Lymphadenopathy Malignancies - Kaposi sarcoma, leukemias, lymphomas, metastases, skin neoplasms Infections -
venereum, primary and ... toxoplasmosis Autoimmune ... Dermatomyositis, rheumatoid arthritis ... disease, systemic lupus ... sarcoidosis Iatrogenic causes
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 Causes of Myocarditis 1. Infectious Myocarditis • Bacterial - Staphylococcus, Streptococcus, Pneumococcus, Meningococcus, Gonococcus, Salmonella, Corynebacterium
Causes of Myocarditis ... Associated with autoimmune ... disorders: Systemic lupus ... erythematosus, rheumatoid arthritis ... more commonly cause
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... usually IgG) (e.g. lupus ... disease, Copper and ... Extravascular #Causes ... differential #diagnosis #hematology
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