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diagnosis differential management oncology syndrome workup approach causes disease gout vasculitis activation classification cppd degenerative dermatologic effusions erythematosus gpa granulomatosis
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #joint #pain #skin ... differential #diagnosis #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Pain History ... : Is the pain from ... • Ligament • Bone ... the subchondral bone ... #Pain #MSK #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... XR, MRI to dx and ... Osteomyelitis / Septic Arthritis ... #Joint #Pain #SickleCell ... diagnosis #causes #hematology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
with temporal arteritis ... and/or joint aches ... • +ANA, +Anti-Smith ... differential #diagnosis #comparison ... #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... Lyme), reactive arthritis ... #Joint #Pain #MSK ... #rheumatology #
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
, joint, and skin ... nonerosive inflammatory arthritis ... • Bone and joint ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis ... - Autoimmune Rheumatologic ... Joint #pain #Differential ... #Diagnosis #MSK ... #rheumatology #
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
nociceptors -> Pain ... in Rheumatoid arthritis ... , Lupus, etc) -> ... #Degenerative #Comparison ... #Versus #MSK #JointDisease
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... • Fever is the main ... SJIA], systemic lupus ... Diagnosis #Management #Hematology ... #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Splenic Marginal Zone ... TMA • Marginal zone ... Scleromyxedema (CNS+GI+CVS+joints ... to cold IgG • Lupus ... Paraproteinemias #Hematology
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