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diagnosis differential erythematosus hematology sle symptoms syndrome systemic vasculitis behcet classification hemophagocytic hlh joint lymphohistiocytosis macrophage mas monoarthritis monoarticular msk
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... lesions Abdominal pain ... (20%) Renal disease ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... • Systemic lupus ... • Fever is the main ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
noninflammatory Signs ... - Autoimmune Rheumatologic ... Disease OLIGOARTHRITIS ... burgdorferi (Lyme disease ... Diagnosis #MSK #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, inflammatory arthritis ... Non-autoimmune rheumatologic ... : • Joint pain ... Chronic B-cell activation ... Erythematosus #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... GCA (Giant Cell Arteritis ... tract: Abdominal pain ... involvement, abdominal pain ... Differential #Diagnosis #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
SLE, Reactive arthritis ... Nonsurgical abdominal pain ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... inflammation Others: • Lupus ... such as systemic lupus ... purpura: strong sign ... differential #diagnosis #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... age, however the disease ... Diagnosis: HLH signs ... agent are the main ... Lymphohistiocytosis #diagnosis #management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Excessive activation ... or without back pain ... • Bilateral signs ... MCTD - Bechet disease ... Myelitis #diagnosis #management
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