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diagnosis differential syndrome joint symptoms vasculitis activation approach behcet classification erythematosus hematology macrophage mas monoarthritis myelitis neurology oligoarthritis oligoarticular polyarthritis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
noninflammatory Signs ... • SLE • Psoriatic ... #Diagnosis #MSK ... #rheumatology # ... Monoarticular #Monoarthritis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... lesions Abdominal pain ... (20%) Renal disease ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
spondyloarthropathies, lupus ... Joints Involved: Monoarticular ... Chronic = RA, SLE ... #Joint #Pain #MSK ... #rheumatology #
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
: SLE, Reactive ... Nonsurgical abdominal pain ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... purpura: Strong sign ... tract: Abdominal pain ... involvement, abdominal pain ... Differential #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... • Fever is the main ... erythematosus [SLE ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... such as systemic lupus ... purpura: strong sign ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Membranoproliferative GN ... phenomenon (16%) MSK ... Arthralgia and Arthritis ... #Diagnosis #Management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
or without back pain ... • Bilateral signs ... Evaluate for NMO, SLE ... Disorders: - SLE ... Myelitis #diagnosis #management
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