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diagnosis differential vasculitis antiphospholipid autoimmune classification glomerulonephritis hematology hypercoagulable myopathy myositis rapidly rpgn syndrome vasculitides workup
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Complement: Post-strep GN ... , Lupus Nephritis ... Purpura Anti-GBM antibodies ... #rheumatology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid Syndrome (APLS ... Hypercoagulable Workup Algorithm ... maternal chromosomal causes ... excluded Testing: • Lupus ... #diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
proteinuria, rapidly progressing ... GN • New pulmonary ... tract, and often causes ... purpura: strong sign ... C-ANCA) pattern: antibodies
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... • Conduction system ... statins - probably caused
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