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differential treatment barre summary tb tuberculosis algorithm alkaline als amyotrophic coccidioides coccidioidomycosis disorders encephalopathy fungal gbs guillainbarre hepatology hyophosphatasia inflammatory
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Weakness • Spinal Cord ... Motor Nerves: ALS ... Poliomyelitis, Guillain-Barre ... #differential #diagnosis ... #neurology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... : • Immune response ... #diagnosis #management ... #treatment #neurology
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
meninges in spinal cord ... lesion Pott's Disease ... Reconstitution Inflammatory Syndrome ... • Caused by immune ... #Tuberculosis #diagnosis
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... of injury • Gait ... Causes: 1. ... MCTD, Sjogren syndrome ... #neurology #differential
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... than one after symptom ... the underlying pathophysiology ... #diagnosis #management ... #neurology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
Pott's Disease in ... extrapulmonary cases ... Clinical Signs ... decreased reflexes Pathophysiology ... should be done in ALL
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... Malnutrition • Wilson's disease ... mineralization Symptoms ... ) - Waddling gait ... Phosphatase: • Other causes
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Transverse Myelitis - Clinical ... Bilateral signs and/or symptoms ... • Infectious causes ... #management #neurology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... survival is 93-95% Pathophysiology ... activity → local immune ... renal failure Clinical ... Pulmonary: dyspnea
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... cells are the immune ... multiple spinal cord ... fasciculations Common Symptoms ... #diagnosis #management
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