11 results
Giant Cell (Temporal) Arteritis

Dr. Ann Marie Kumfer @AnnKumfer

#GiantCell #Temporal #Arteritis #Diagnosis #Management #GCA #rheumatology
Giant Cell (Temporal ... #GiantCell #Temporal ... #Arteritis #Diagnosis ... #Management #GCA ... #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... in literature (NEJM ... cases (Cornelia NEJM ... them, but urgent rheumatology ... #Management
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
- Arteritis temporalis ... (giant-cell arteritis ... Kawasaki disease - Primary ... #Rheumatology # ... Diagnosis
Giant Cell Arteritis (Polymyalgia Rheumatica and Cranial Arteritis): Pathogenesis and Clinical Findings
 - Morning Stiffness (>1
Giant Cell Arteritis ... Muscle Aching (Primarily ... Weight Loss #Temporal ... CranialArteritis #Pathophysiology ... Signs #Symptoms #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Auto-amplification loop Diagnosis ... assessment+++ Primary ... #management #treatment ... #summary #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Treatment: • Treat primary ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... and Superficial temporal ... with GCA or as primary ... Rash, arthritis Primary ... #Rheumatology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Lung abscess Primary ... : Symptomatic Primary ... Tuberculosis Diagnosis ... #Management #Treatment
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Vaginal dryness • Primary ... Sjogren's Syndrome Diagnosis ... ab (specific in primary ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Lung abscess Primary ... : Symptomatic Primary ... Tuberculosis Diagnosis ... #Management #Treatment