10 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Manifestations: Malar rash ... Alopecia, oral ulcers ... Positive in 60-80% of cases ... life-threatening • Treatment ... : Chronic disease
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
) Differential Diagnosis ... Oral aphthae : SLE ... • Arthritis: SLE ... Arthritis, AS Treatment ... Syndrome #diagnosis #management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Discontinuation of causal ... Manifestations: Malar rash ... Alopecia, oral ulcers ... : Chronic disease
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... effusion), mouth (ulcers ... nose (epistaxis), skin ... Nephrocalcinosis causes ... #Algorithm #differential
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
rash in association ... Edema in 70% of cases ... Skin involvement ... Resolution > 15 days Differentials ... : symptomatic treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... livedo reticularis, ulcers ... mucositis - Rash ... genital aphthous ulcers ... vasculitis, and SLE
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... , such as SLE, atherosclerotic ... , mucositis • Rash ... tract, and often causes
Monkeypox

What?
Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus
Viral zoonotic disease that is
Viral zoonotic disease ... that is caused ... soles • Oral ulcers ... Respiratory distress Treatment ... MPOX #Diagnosis #Management
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... Muscle atrophy may cause ... had more severe disease ... positive patients Treatment ... #diagnosis #management
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
24%) • Mouth ulcers ... sweats (28%) • Skin ... rash (48%) • ... • New onset SLE ... ART to slow HIV disease