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Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: • Behçet Syndrome ... to exclude are infections ... purpura: strong sign ... Cryoglobulins • HIV ... differential #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Pathophysiology ... endothelial damage • Induce ... Imaging: CXR- pulmonary ... : >3 symptoms, or ... Diagnosis: Infection
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... purpura: Strong sign ... pain • HTN • ... • Behcet syndrome
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... in HIV - Differential ... • CT: Halo sign ... #Infections #HIV ... #AIDS #pulmonary
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
respiratory distress syndrome ... Pleuritic chest pain ... failure - Infectious ... #Pulmonary #diagnosis ... #management #Toxicology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
or without back pain ... • Bilateral signs ... and/or symptoms ... simplex virus, HIV ... #differential
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
3) Abdominal, ... yeast • At risk: AIDS ... Aspergillosis Pathophysiology ... pulmonary infection ... #Management #Infections