340 results
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... Inherited (AR) hypokalemic ... cotransporter • Gitelman's ... Pseudo Bartter-Gitelman ... Magnesium #Gitelman
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Differentiating Gitelman ... krithicism #Gitelman ... Algorithm #nephrology #hypokalemia
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Hypokalemia Differential ... tubular acidosis • Gitelman's ... Hypothermia • Hypokalemic ... amzn.to/2LmUODZ #Hypokalemia
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology Gitelman ... H+ secretion → Hypokalemia ... dr_missyhanna #Gitelman
Gitelman Syndrome - Management
Treatment includes
 - Electrolyte replacement - K & Mg, preferably Cl salts
Gitelman Syndrome ... In persistent hypokalemia ... Ramesh @SRameshMD #Gitelman
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Bartter syndrome, Gitelman ... @priti899 #Hypokalemia
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
patients with hypokalemia ... • Cell shift: Hypokalemic ... Bartter syndrome, Gitelman ... syndrome #hypokalemia
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Defining the cause of hypokalemia ... Hypomagnesemia-induced hypokalemia ... Bartter's syndrome, Gitelman's ... Cushing's syndrome #hypokalemia
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... Before evaluating hypokalemia ... in evaluating hypokalemia ... Bartter syndrome, Gitelman ... @krithicism #Hypokalemia
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... ß-Adrenergic agonists, Hypokalemic ... congenital), Thyrotoxic hypokalemic ... diuretic use), Gitelman's ... or induced) #Hypokalemia