11 results
Primary vs Secondary Adrenal Insufficiency - Pathophysiology
Primary AI = adrenal glands themselves are the problem. This
Secondary Adrenal Insufficiency ... Primary AI = adrenal glands ... the pituitary gland ... limited adrenal stimulation ... Pathophysiology #endocrinology
Adrenal Insufficiency Diagnosis Algorithm
Clinical features: 
 - Weight loss, anorexia, Weakness, fatigue, GI distress
 - Hypotension,
Adrenal Insufficiency ... due to high ACTH stimulating ... with cosyntropin stimulation ... #Cosyntropin #Stimulation ... #StimTest #Endocrinology
Adrenal Insufficiency Algorithm - Cosyntropin Stimulation Test
T-1m: Baseline cortisol drawn
T0: 250 µg cosyntropin given IV
T30m: Repeat
Adrenal Insufficiency ... - Cosyntropin Stimulation ... BCM_InternalMed #Adrenal #Insufficiency ... #Cosyntropin #Stimulation ... #endocrinology
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Diagnosis Adrenal Insufficiency ... Test: Cosyntropin Stimulation ... ) #Adrenal #Insufficiency ... Diagnosis #ACTH #Stimulation ... #Endocrinology
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
: • ACTH stimulation ... to the adrenal gland ... : • ACTH stimulation ... of the adrenal glands ... diagnosis #testing #endocrinology
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Adrenal Insufficiency ... hormone (ACTH) stimulation ... Response - Adrenal insufficiency ... Primary adrenal insufficiency ... Diagnosis #Algorithm #endocrinology
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
-> Continuous stimulation ... thyroglobulin, Thyroid gland ... Dysphagia, Thyroid gland ... pathophysiology #endocin #endocrinology
Adrenal Insufficiency Diagnosis Algorithm
Test 1: Baseline AM Cortisol 
 - Beware of major normal value
 -
Adrenal Insufficiency ... ) Test 2: ACTH Stimulation ... BCM_InternalMed #Adrenal #Insufficiency ... Diagnosis #Algorithm #endocrinology
Infectious Causes of Adrenal Insufficiency
Anatomical distribution of vessels to the adrenal makes the gland prone to
Causes of Adrenal Insufficiency ... adrenal makes the gland ... behind the adrenal gland ... Causes #Adrenal #Insufficiency ... differential #diagnosis #endocrinology
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... AI #Adrenal #Insufficiency ... Algorithm #ACTH #Stimulation ... #Test #Endocrinology