14 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome:
 - Acute poststreptococcal 
glomerulonephritis 
 - Rapidly progressive
Glomerular Diseases ... Nephrotic Syndromes ... #Glomerular ... #Diseases #Nephritic ... #Nephrology #Diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... diabetes)) #Glomerular ... #Diseases #Nephritic ... #Nephrotic #Syndromes
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
/nephritic syndromes ... the patient have glomerular ... hematuria (RBC casts ... #Syndrome #Comparison ... #Diagnosis
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
RBCs and/or RBC casts ... • Thin GBM disease ... • Hereditary nephritis ... • Pauci-immune disease ... and >3.5g/day (nephrotic
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... red - cells Non-glomerular ... Dysmorphic red cells - Glomerular ... glomerular disease ... #nephrology #casts
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
- TTP/HUS • Glomerular ... disease - Post-infectious ... Tubulointerstitial disease ... Acute interstitial nephritis ... #diagnosis #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
cell/white cell casts ... impairment), heart disease ... cluster, the diseases ... clusters because nephritic ... #nephrotic #syndrome
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... Disease Associations ... Advanced kidney disease ... tubulointerstitial nephritis ... tuberculosis Fatty - Nephrotic
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... dysmorphic RBC, RBC casts ... formation along glomerular ... (Dense deposit disease ... glomerulopathy, radiation nephritis
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... of Glomerular Bleeding ... basement membrane disease ... : - RBC casts ... disease Renal