18 results
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
vascular supply; glomerular ... and interstitial disease ... GBM, Glomerular ... #Diagnosis #AKI ... Injury #Differential
Kidney Syndromes - A Guide to Compartmentalize the Etiologies of Kidney Disease
1) Tubule and interstitium
2) Vasculature
3)
Disease 1) Tubule ... Vasculature 3) Glomerulus ... #Syndromes #Differential ... #Diagnosis #Causes ... #Failure #Injury
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Acute Kidney Injury ... (AKI) - Differential ... Diagnosis Framework ... • Vascular • Glomerular ... #Injury #Differential
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Drug Induced Kidney ... Vitamin C • Glomerular ... Disease: Drug induced ... vasculitis, TMA ... #diagnosis #algorithm
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... - Small vessel vasculitis ... - TTP/HUS • Glomerular ... #AKI #Acute #Kidney ... #diagnosis #nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... - Skin, glomeruli ... : glomerular ischemia ... purpura: strong sign ... differential #diagnosis
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... Diagnosis for Pulmonary ... sclerosis • Anti-Glomerular ... Renal #Syndrome #differential ... #diagnosis #nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... Immune mediated injury ... • Causes of Glomerular ... of glomerular hematuria ... Suggestive of glomerular
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... • Limited to Kidney ... With associated pulmonary ... #differential # ... diagnosis #algorithm
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease)

What is it? A small vessel vasculitis with circulating antibodies directed
A small vessel vasculitis ... directed against the glomerular ... hemorrhage Diagnosis ... following: Serum, Kidney ... #nephrology #pulmonary