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differential nephrology vasculitis algorithm management syndromes urology acute aki arterial arthritis blood embolism erythematosus glomerulonephritis hematology kidney lupus progressive proteinuria
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... hematuria. ... diabetes)) #Glomerular ... #Diseases #Nephritic ... #Classification
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
• Calculi Glomerular ... • Thin GBM disease ... • Hereditary nephritis ... • Pauci-immune disease ... and >3.5g/day (nephrotic
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... of Glomerular Bleeding ... basement membrane disease ... • Signs of glomerular ... disease Renal
Causes of Hematuria - Differential Diagnosis Renal: - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
Causes of Hematuria ... Renal: - Glomerular ... - Interstitial nephritis ... necrosis, Sickle cell disease ... #Diagnosis #Causes
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Intrinsic renovascular disease ... - TTP/HUS • Glomerular ... disease - Post-infectious ... Tubulointerstitial disease ... Acute interstitial nephritis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Skin, glomeruli ... disease, and ocular ... : - Kidneys: glomerular ... (Granulomatous disease ... atherosclerotic disease
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... Inflammatory eye disease ... injury), Coags ... Goodpasture's cause ... hypercellular glomeruli
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
peritonitis Lupus nephritis ... abnormalities (non-nephrotic ... ) • Frank nephritis ... (nephrotic-range ... suspicion for nephritis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Post-strep GN, Lupus Nephritis ... With associated pulmonary ... involvement: Anti-GBM Disease
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Parenchymal lung disease ... , Pleural disease ... , Airways disease ... and peptic ulcer disease ... Tubulo-interstitial nephritis
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