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diagnosis differential renal aki vasculitis acute algorithm classification management anti antigbm arterial basement blood druginduced embolism failure giomeruiar glomerulonephritis goodpastures
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
kidney injury (AKI ... vascular supply; glomerular ... and interstitial disease ... GBM, Glomerular ... #Sites #Nephrology
Kidney Syndromes - A Guide to Compartmentalize the Etiologies of Kidney Disease 1) Tubule and interstitium 2) Vasculature 3)
Kidney Syndromes ... Disease 1) Tubule ... Vasculature 3) Glomerulus ... #Diagnosis #Causes ... #Failure #Injury
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... - Small vessel vasculitis ... - TTP/HUS • Glomerular ... tubular necrosis (causes ... #diagnosis #nephrology
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... Immune mediated injury ... of Glomerular Bleeding ... of glomerular hematuria ... Suggestive of glomerular
Drug Induced Kidney Injury • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy • Osmotic
Drug Induced Kidney ... Vitamin C • Glomerular ... Disease: Drug induced ... vasculitis, TMA ... diagnosis #algorithm #nephrology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
ANCA-positive vasculitis ... ANCA-negative vasculitis ... IgA-associated vasculitis ... sclerosis • Anti-Glomerular ... differential #diagnosis #nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... - Skin, glomeruli ... : glomerular ischemia ... purpura: strong sign ... differential #diagnosis #rheumatology
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
A small vessel vasculitis ... directed against the glomerular ... following: Serum, Kidney ... AntiGBM #diagnosis #nephrology ... #pulmonary
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... • Limited to Kidney ... With associated pulmonary ... involvement: Anti-GBM Disease
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... life-threatening diseases ... quantify renal injury ... Goodpasture's cause ... hypercellular glomeruli
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