7 results
Comparison of Fever Algorithms for Infants <3 months old

AGE, INCLUSION, TESTS 
REQUIRED, "LOW RISK" CRITERIA, TREATMENT,
Comparison of Fever ... Algorithms for ... of low-risk criteria ... #EBM #Fever ... #Table #Performance
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... IFN-y) → Excessive activation ... • Clinical: fever ... , Hb), Hepatic dysfunction ... biologics (CMV +++, EBV
Guide to systemic mastocytosis

Criteria for diagnosis: at least 1 major and 1 minor or 3 minor
mastocytosis Criteria ... minor or 3 minor criteria ... cytopenias or meeting criteria ... without organ dysfunction ... hemepath #pathology #algorithm
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... - Nonremitting fever ... nervous system (CNS) dysfunction ... Histopathologic criteria ... MAS #Macrophage #Activation
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bowel or bladder dysfunction ... • Excessive activation ... Autonomic Dysfunction ... Diagnostic Criteria ... Brucellosis - Dengue, EBV
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... , organ dysfunction ... Infections (e.g., EBV ... Diagnostic Criteria ... of 8 HLH-2004 criteria
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
or family - Ever ... Performance thorough ... event, follow ACC algorithm ... with valvular dysfunction ... or LV dysfunction