4 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... • Clinical: fever ... , Hb), Hepatic dysfunction ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... nervous system (CNS) dysfunction ... Histopathologic criteria ... MAS #Macrophage #Activation ... Syndrome #Diagnosis #Management
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
Preoperative Risk Evaluation ... Performance thorough ... event, follow ACC algorithm ... or LV dysfunction ... medical and surgical management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... cytopenias and organ dysfunction ... , organ dysfunction ... Diagnostic Criteria ... of 8 HLH-2004 criteria