6 results
Comparison of Fever Algorithms for Infants <3 months old

AGE, INCLUSION, TESTS 
REQUIRED, "LOW RISK" CRITERIA, TREATMENT,
Comparison of Fever ... Algorithms for ... of low-risk criteria ... #EBM #Fever ... #Table #Performance
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... - Nonremitting fever ... nervous system (CNS) dysfunction ... Histopathologic criteria ... #Activation #Syndrome
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... of macrophages ... • Clinical: fever ... , Hb), Hepatic dysfunction
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
with excessive macrophage ... activation and ... genetic immune dysfunction ... following: • Fever
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... , organ dysfunction ... termed MAS-HLH: Macrophage ... Diagnostic Criteria ... of 8 HLH-2004 criteria
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
or family - Ever ... Performance thorough ... event, follow ACC algorithm ... with valvular dysfunction ... or LV dysfunction