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management diagnosis hematology fever stratification antibiotics cancer differential febrile hemophagocytic hlh hyperkalemia infant lp lymphohistiocytosis medications neurology oncology pediatrics peds
Comparison of Fever Algorithms for Infants <3 months old AGE, INCLUSION, TESTS REQUIRED, "LOW RISK" CRITERIA, TREATMENT,
REQUIRED, "LOW RISK ... " CRITERIA, TREATMENT ... , Performance of ... low-risk criteria ... #EBM #Fever
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
, Hb), Hepatic dysfunction ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Unknown cause Treatment ... diagnosis #management #treatment
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... this group as well ... components of the algorithm ... source must be: - Well ... Infant #StepByStep #Algorithm
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
Preoperative Risk ... Performance thorough ... event, follow ACC algorithm ... with valvular dysfunction ... or LV dysfunction
Emergency Management of Hyperkalemia in Adults Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach •
ECG and rate of rise ... Shift K+ into cells ... prevent further rise ... Hyperkalemia #management #algorithm ... #treatment
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Release from blast cells ... • Induce blast cell ... Attempt if high risk ... severe APLS, organ dysfuxtion
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). Mild infection: for
IDSA Algorithm for ... 12 000 or <400 cells ... oral antibiotic treatment ... evidence of organ dysfunction ... #SSTIs #Algorithm
The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an
tranexamic acid for the treatment ... in reducing the risk ... commenced, as well ... interventions #EBM
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
marrow or stem cell ... unclear, endothelial dysfunction ... Risk factors 3. ... elevated white blood cell ... epilepticus Treatment
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... Reed-Sternberg cells ... Hodgkin Lymphoma Risk ... • History of EBV ... Hodgkin Lymphoma Treatment
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