11 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
II - IgG or IgM ... during hemolytic disease ... Type Ill - IgG and ... #Classification ... Diagnosis #Reactions #Table
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
IGG-4 RELATED DISEASE ... - Organ dysfunction ... progressive organ dysfunction ... • Pancreas: Type ... complement • Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... - Mediators: IgG ... reaction, Haemolytic disease ... #allergy #table ... #classification
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
conjunctivitis Type ... Mediator: IgM + IgG ... Gravis, Graves' Disease ... Immunological Mediator: IgG ... #Classification
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... protein receptor type ... activin A receptor type ... Systolic dysfunction ... Diastolic dysfunction
Shock Classification
Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Classification ... END-ORGAN DYSFUNCTION ... • Most common type ... #Types #diagnosis ... warm #wet #dry #table
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
Performance thorough ... with valvular dysfunction ... or LV dysfunction ... Risk Stratify Type ... What is the type
Von Willebrand Disease Classification
Type 1 (Accounts for ~3/4 of cases):
 • Defect: Quantitative defect (i.e. not
Von Willebrand Disease ... Classification ... Qualitative defect (i.e. dysfunctional ... VonWillebrand #Disease ... #Classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... Classification: ... ) • Kikuchi disease ... • Type-I Interferonopathies ... mild cognitive dysfunction
DEMYELINATING DISEASES OF THE CENTRAL NERVOUS SYSTEM

What Are Demyelinating Diseases?
• Conditions that damage myelin, the protective
Serologies: AQP4-IgG ... , MOG-IgG ... • Clinical Types ... Persistent MOG-IgG ... bladder/bowel dysfunction