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diagnosis treatment hematology rheumatology tb tuberculosis hemophagocytic hlh latenttb lymphohistiocytosis checklist differential hemeonc msk neurology orthopedics perioperative syndrome video workup
Clarke's Test (Patellar Grind Test) Indicates Patellofemoral dysfunction. - Patient with knee in extension. Push posterior on
Clarke's Test (Patellar ... Grind Test) ... Patellofemoral dysfunction ... patient to perform active ... Patellar #Grind #clinical
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 Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Endogenous reactivation ... characteristic features Clinical ... Tuberculin skin test ... Inhibitor: • Risk of reactivation ... TB #Diagnosis #Management
Tuberculosis Testing LATENT TB • LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
result with no clinical ... manifestations of active ... decrease the risk for reactivation ... of developing active ... years of age ACTIVE
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Endogenous reactivation ... characteristic features Clinical ... Tuberculin skin test ... Inhibitor: • Risk of reactivation ... TB #Diagnosis #Management
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
complex → plt activation ... Diagnosis: • Clinical ... approach for post-test ... : Confirmatory test ... non-heparin A/C if clinical
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... accumulation of clinical ... Assessment • Clinical ... , Hb), Hepatic dysfunction ... Lymphohistiocytosis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... excessive macrophage activation ... genetic immune dysfunction ... absent NK cell activity ... Lymphohistiocytosis #diagnosis #management
SEPSIS AND SEPTIC SHOCK DEFINITION AND PATHOPHYSIOLOGY • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
cytokines, complement activation ... CLINICAL RECOGNITION ... CLINICAL FEATURES ... and molecular tests ... INITIAL MANAGEMENT
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Excessive activation ... Transverse Myelitis - Clinical ... negative, MOG-IgG test ... Herpes zoster, West ... Myelitis #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Fever is the main clinical ... nervous system (CNS) dysfunction ... Liver function tests ... Syndrome #Diagnosis #Management
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