6 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
chromosome 21) Signs ... Executive planning dysfunction ... seizure, primitive reflexes ... AlzheimersDisease #Dementia #pathophysiology ... geriatrics #diagnosis #signs
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
• Mutism Pathophysiology ... Severe injury/dysfunction ... • Gag reflex ... • Cough reflex ... • Examine for signs
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Upper Extremity Dysfunction ... deficiencies -> Sphincter dysfunction ... bladder and rectal reflex ... Syndromes #diagnosis #pathophysiology ... #signs #symptoms
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
lumbar spine Signs ... of normal leg reflexes ... bladder/bowel dysfunction ... Syndrome #MSK #pathophysiology ... diagnosis #symptoms #signs
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bowel or bladder dysfunction ... monophasic Pathophysiology ... Spasticity - Reflexes ... Autonomic Dysfunction ... • Bilateral signs
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
• Symptoms and signs ... Bowel and bladder dysfunction ... • Abnormal reflexes ... differential #algorithm