11 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... IFN-y) → Excessive activation ... , Hb), Hepatic dysfunction ... Unknown cause Treatment ... inhibitors under evaluation
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
Preoperative Risk Evaluation ... Performance thorough ... event, follow ACC algorithm ... with valvular dysfunction ... or LV dysfunction
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... nervous system (CNS ... ) dysfunction • ... Treatment: • Corticosteroids ... MAS #Macrophage #Activation
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... HIV-Associated CNS ... infections result from reactivation ... presentation, temporal evolution ... Antimicrobial treatment
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
and infects the CNS ... -> microglial activation ... Behavioral • Motor dysfunction ... Treatment: • HAART ... treatment • Cognitive
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bowel or bladder dysfunction ... • Excessive activation ... that results in CNS ... Autonomic Dysfunction ... Transverse Myelitis Treatment
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
and Management Algorithm ... Entacavir, tenofovir vs ... absent the risk of reactivation ... HepatitisB #HBV #Algorithm ... Diagnosis #Management #Treatment
Severe Heart Failure & Cardiogenic Shock - Management Checklist 
Evaluation 
 - EKG & echocardiography
Management Checklist Evaluation ... Consider BiPAP (vS ... severe or w/ organ dysfunction ... Revascularization, treatment
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
The Neurological Evaluation ... Severe injury/dysfunction ... ascending reticular activating ... /flaccid limbs vs
Cyclic Vomiting Syndrome (CVS) - Management Algorithm
General Approach:
 - Identify and avoid triggers
 - Good sleep
Vomiting Syndrome (CVS ... ) - Management Algorithm ... use, autonomic dysfunction ... Topiramate and CoQ10 #CVS ... #Treatment