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HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
and infects the CNS ... -> microglial activation ... Behavioral • Motor dysfunction ... Treatment: • HAART ... treatment • Cognitive
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
Preoperative Risk Evaluation ... Performance thorough ... event, follow ACC algorithm ... with valvular dysfunction ... or LV dysfunction
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Principles of HIV-Associated ... infections result from reactivation ... presentation, temporal evolution ... Antimicrobial treatment ... Periventricular regions; associated