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diagnosis hemophagocytic lymphohistiocytosis evaluation hematology hemeonc perioperative preop preoperative rheumatology risk stratification summary treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , Hb), Hepatic dysfunction ... biologics (CMV +++, EBV ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... cytopenias and organ dysfunction ... hyperinflammatory syndrome caused ... , organ dysfunction ... Infections (e.g., EBV
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
or family - Ever ... Performance thorough ... event, follow ACC algorithm ... or LV dysfunction ... medical and surgical management
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