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diagnosis anemia hemolytic agglutinin aspergillus betadglucan causes comparison disease extravascular fungal galactomannan hemolysis intravascular workup
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Diagnosis Algorithm ... Warm AIHA • Cold ... perfringens - Complement-Mediated ... • Cold AIHA ... #Causes #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Positive Coombs testing ... post infectious setting ... younger pts) Differential ... temperatures by fixing complement ... hemolytic #anemia #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... Agglutination - Cold ... #workup #hematology ... #testing
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers ... infection (IFI) in hematologic ... BAL GM does not differentiate ... Frozen ice-pops (in setting ... Dong #Fungal #Biomarkers
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