12 results
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Differential Diagnosis Algorithm ... , hypoglycemia Testing ... hormone (ACTH) stimulation ... Baseline plasma ACTH Low ... • Low or normal
Adrenal Insufficiency Algorithm - Cosyntropin Stimulation Test
T-1m: Baseline cortisol drawn
T0: 250 µg cosyntropin given IV
T30m: Repeat
Adrenal Insufficiency ... Algorithm - Cosyntropin ... Stimulation Test ... #Testing #Algorithm ... #Cosyntropin #Stimulation
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... Diagnosis Algorithm ... then go to stim testing ... primary AI - Low ... #ACTH #Stimulation
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Diagnosis Adrenal Insufficiency ... - Algorithm ... specificity for AI (but low ... require Cosyntropin testing ... - Low ACTH is
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia Algorithm ... Hypothyroidism, Adrenal insufficiency ... Cerebral salt wasting ... Primary polydipsia, Low ... #diagnosis #sodium
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Differential Diagnosis Algorithm ... Uric Acid - Low ... Acid → renal salt wasting ... #nephrology #sodium ... #low #uricacid
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
between 8 and 9 AM - Low ... aldosterone - Low ... between 8 and 9 AM - Low ... Plasma ACTH - Low ... laboratory #diagnosis #testing
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... : SIADH, Renal Sodium ... can be high or low ... Hypothyroidism, Adrenal Insufficiency ... Cerebral Salt Wasting
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
PRA • ↓ Serum sodium ... • Weakness • Low-grade ... ACTH • ↓ Serum sodium ... tests: - Check sodium ... present - ACTH stimulation
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Cerebral salt wasting ... Hypothyroidism, Low ... #Hyponatremia #algorithm ... #diagnosis #sodium ... #low #nephrology