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differential aflp chemistry chronic cirrhosis classification drug fatty grading hepatic idiosyncratic induced injury interpretation lfts obgyn obstetrics pathophysiology pregnancy rvalue
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
ACLF) Clinical Guidelines ... disease, liver ... Injury (DILI) ... #Cirrhosis #Hepatology ... #management #diagnosis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... disease 6-9 mo ... #Management #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... liver failure rapidly ... hypoglycemia, encephalopathy ... 10x ULN), ↑Tbili/Dbili ... #Pregnancy #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Failure ( ... ALF): • Liver ... INR > 1.5 • Encephalopathy ... #chemistry #diagnosis ... #differential #Hepatology
Hepatic Encephalopathy - Diagnosis and Management Summary Definition: • Alteration in brain function manifested by neuropsychiatric symptoms
• Caused by liver ... other causes of neurologic ... over course of disease ... colonic bacteria • Guidelines ... #hepatology
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