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diagnosis management hematology differential erythematosus hemophagocytic hlh lupus lymphohistiocytosis sle systemic vasculitis arthritis behcet centralretinalartery chronic classification crao cryofibrinogenemia hemeonc
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Pathogenesis and clinical ... • Inflammatory Disease ... • Hematologic Disease ... ophthalmology #diagnosis #signs ... #symptoms
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... (SVC/IVC occlusion ... (Clinical Dx). ... diagnosis #management #signs ... #symptoms #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... Physical Exam/Signs ... cells can indicate disease ... • Richter’s Syndrome
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... pulmonary emboli, and ocular ... thrombi including retinal ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... disease (30%): ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
and Symptoms • ... Ocular: Keratoconjunctivitis ... Pericarditis • Renal ... Thrombocytosis, Felty's syndrome ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• Cogan Syndrome ... reactions, and vaso-occlusive ... Presentation - Systemic Symptoms ... purpura: strong sign ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... reactions, and vaso-occlusive ... purpura: Strong sign ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Erythematous, macular ... Non-autoimmune rheumatologic ... Clinical Features ... Induced Lupus: • Symptoms
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... age, however the disease ... Diagnosis: HLH signs ... and symptoms can
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