9 results
Kaposi Sarcoma Herpes Virus (KSHV)

By Dr. Sara Dong @swinndong via #IDFellowCase
#ID  #Infectious Diseases  #Infections
#Differential
Kaposi Sarcoma Herpes ... #Differential #Ddx ... #Diagnosis #KSHV ... #HHV #lymphoproliferative ... #KICS
KSHV Inflammatory Cytokine Syndrome (KICS)

By Dr. Sara Dong @swinndong  via #IDFellowCase
#ID  #Infectious Diseases
Cytokine Syndrome (KICS ... #Differential #Ddx ... #Diagnosis #KSHV ... #HHV #KICS #Kaposi
HHV8/KSHV-reIated diseases: From Cellular Proliferation to Hyperinflammation
Kaposi sarcoma (KS):
 • Target organs: Ubiquitous (cutaneous and mucosal
HHV8/KSHV-reIated ... Hyperinflammation Kaposi ... Light chain: - HHV8 ... de Fremont #HHV8 ... diseases #comparison #diagnosis
Infection-Related Cancers
Viruses:
 • HPV - Cervical, anogenital, head and neck, skin cancer
 • HTLV-1 - Adult
Cancers Viruses: • HPV ... - NHL, Kaposi's ... carcinoma • HHV ... -8 - Kaposi's sarcoma ... #differential #diagnosis
Post-Intensive Care Syndrome (PICS)
Symptoms of PICS:
 - Physical Domain: Generalized weakness, Fatigue, Difficulty walking
 - Cognitive
RISK FACTORS - ICU ... of the ABCDEF bundle ... screening (CAM-ICU ... #diagnosis #management ... #criticalcare #icu
KSHV Inflammatory Cytokine Syndrome (KICS)
Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
Cytokine Syndrome (KICS ... Definition for KICS ... Cytokine #Syndrome #Kaposi ... #diagnosis #management ... #hhv8
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... hemophagocytosis = additional diagnostic ... Virus (EBV, CMV, HHV8 ... of emergency, ICU ... Lymphohistiocytosis #diagnosis
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
of a previously diagnosed ... IRIS: Generally Diagnosis ... No specific diagnostic ... • Kaposi sarcoma ... , HHV8 - Worsening
Cryptococcal meningitis on T2 MRI
30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Diagnosis? ... DDX Tb meningitis ... organism (soap bubble ... drained at time of diagnosis ... to normalize ICP