13 results
KSHV Inflammatory Cytokine Syndrome (KICS)

By Dr. Sara Dong @swinndong  via #IDFellowCase
#ID  #Infectious Diseases
KSHV Inflammatory ... Cytokine Syndrome ... #Differential # ... Diagnosis #KSHV #HHV ... #KICS #Kaposi
Kaposi Sarcoma Herpes Virus (KSHV)

By Dr. Sara Dong @swinndong via #IDFellowCase
#ID  #Infectious Diseases  #Infections
#Differential
Kaposi Sarcoma Herpes ... Diseases #Infections ... #Differential # ... Diagnosis #KSHV #HHV ... lymphoproliferative #KICS
Causes of Encephalopathy - Differential Diagnosis Algorithm
Hyperacute:
 - Primary Neurologic: Vascular (IS, ICH), Seizure, Migraine, Trauma
Encephalopathy - Differential ... Vascular (IS, ICH ... Vascular (SDH), Inflammatory ... paraneoplastic syndromes ... ), Inflammatory,
KSHV Inflammatory Cytokine Syndrome (KICS)
Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
KSHV Inflammatory ... Cytokine Syndrome ... if present Infectious ... #Kaposi #diagnosis ... #management #hhv8
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
that disrupts immune ... production of pro-inflammatory ... Virus (EBV, CMV, HHV8 ... Others: Cellular immune ... of emergency, ICU
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory ... Causes Immune-mediated ... Non-inflammatory ... pachymeningitis • HIV ... noninflammatory #differential
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome ... • Kaposi sarcoma ... , HHV8 - Worsening ... Leishmaniasis Differential ... #Syndrome #Differential
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... • Inflammatory ... Polymyositis • Immune ... parainfluenza, Coxsackie, HIV ... #Weakness #Differential
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Reconstitution Inflammatory ... Syndrome (IRIS) ... : • In HIV+, usually ... and not direct infection ... Tuberculosis #diagnosis #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... Necrotizing, pauci-immune ... respiratory tracts Immune ... : - Ocular inflammatory ... to exclude are infections