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KSHV Inflammatory Cytokine Syndrome (KICS)

By Dr. Sara Dong @swinndong  via #IDFellowCase
#ID  #Infectious Diseases
KSHV Inflammatory ... Cytokine Syndrome ... (KICS) By Dr. ... #Differential # ... Diagnosis #KSHV #HHV
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Budd-Chiari syndrome ... - Nephrotic syndrome ... SAAG < 1.1 g/dL) Infections ... Causes #diagnosis #differential ... #hepatology #SAAG
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Ascites - Differential ... Fitz-Hugh-Curtis syndrome ... ), HIV-related, ... Disease, Fulminant Hepatic ... Diagnosis #hepatology
Causes of Acute Onset Fever - Differential Diagnosis Algorithm
Viral:
 • Rhinovirus
 • Influenza Virus
 • Parainfluenza
Onset Fever - Differential ... Coronavirus • HIV ... Continuous Bacteremia Septic ... • Extremity Inflammatory ... Neuroleptic malignant syndrome
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Parenchyma • Infectious ... , D, EBV, CMV, HSV ... obstruction, HELLP Syndrome ... Acute #algorithm #hepatology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Knee Effusions - Septic ... Candidiasis Inflammatory ... arthritis - Inflammatory ... Seronegative Reactive Syndrome
KSHV Inflammatory Cytokine Syndrome (KICS)
Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
KSHV Inflammatory ... Cytokine Syndrome ... if present Infectious ... #KSHV #Inflammatory ... diagnosis #management #hhv8
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Liver Injury: • Hepatic ... vein: Budd-chiari syndrome ... Liver Injury: • Infectious ... diagnosis #algorithm #hepatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... SLE) - Viral infections ... Kasabach-Merritt syndrome ... APLS • Acute Infectious ... • HCV, HBV Not
VIBES Mnemonic - Cirrhosis Management Checklist

V - Volume (Ascites, HRS)
	- Evaluate for Ascites, Edema, Hydrothorax, Hepatorenal
V - Volume (Ascites ... Hydrothorax, Hepatorenal Syndrome ... paracentesis / TIPS I - Infection ... beta-blockers E - Hepatic ... Management #Diagnosis #Hepatology