13 results
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Diagnosis for Hemolytic ... Anemia Intrinsic ... #Anemia #Differential ... #classification ... #hematology
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
thrombocytopenia, Autoimmune Hemolytic ... anemia, Penicillin-induced ... IV Hypersensitivity ... Stevens-Johnson Syndrome ... #Classification
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Disease 3 Types ... Cold Agglutinin Syndrome ... anemia • Cold ... Mycoplasma, EBV, HIV ... #anemia #hematology
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... diseases - HIV ... Schistosomiasis - Chronic hemolytic ... anemia - Persistent ... #Differential #Causes
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... • HCV, HBV Not
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
Inherited Non-hemolytic ... without evidence of hemolysis ... and stress may cause ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
Irritable Bowel ... Syndrome (IBS) - ... • Rome IV Criteria ... and Hepatology ... IBS #Irritable #Bowel
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
hydrocephalus, HIV ... diagnostic workup What type ... - Progressive amnesia ... Aphaso-apraxo-agnosia syndrome ... Differential #Subtypes #Classification
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Compartment syndrome ... 30mmHg) - Severe anemia ... Ethylene glycol - HIV ... #typea #typeb # ... classification
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
and autoimmune hemolytic ... anemia) • Systemic ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome