15 results
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Difficile Infection ... often ordered in reflex ... • Flex-Sig: If ... Bezlotoxumab 10 mg/kg IV ... ciab549 #CDI #Cdiff
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Idiopathic • Infections ... - HIV • Immune ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
test - Cogan sign ... - Peek sign ... immunologic assay - MuSK ... precipitated by: Drugs, infection ... Gravis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... Diagnosis: HLH signs ... : • Infection ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Esophageal Necrosis
Etiology:
 - Ischemia and Gastric Outlet Obstruction with GERD may be inciting events
 - Associated
antibiotic use, infections ... Stevens-Johnson syndrome ... injury (by acid reflux ... : - Treatment of ... Necrosis #diagnosis #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
response preceding infection ... Campylobacter jejuni - HIV ... Decreased / Absent Reflexes ... #diagnosis #management ... #treatment #neurology
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
tibia/fibula) and hip ... progressive inflammatory infection ... cord function and reflex ... bulbocarvenosus reflex ... #treatment
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Albuminuria, nephrotic syndrome ... ulcerated • MSK ... individuals with HIV ... stages #diagnosis #management ... #Treatment
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Multiple Sclerosis Treatment ... • Acute: - IV ... sclerosis #diagnosis #management ... #neurology #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Differential Diagnosis: Infection ... • Steroids: IV ... APML #diagnosis #management ... #hematology #oncology