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differential hematology lupus pulmonary sle systemic vasculitis arteritis autoimmune behcet bronchiectasis classification cll cvid disease fungal gca giantcell hypogammaglobulinemia immunodeficiency
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... • CT: Halo sign ... #Infections #HIV ... #AIDS #pulmonary ... #infectiousdiseases
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
effusion, Restrictive lung ... Demyelinating syndromes ... ) Blood (75%): Anemia ... #signs #symptoms ... #diagnosis #rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... lung disease ... autoimmune hemolytic anemia ... syndrome, HIV) ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
fibromyalgia) • Infections ... PNS and CNS • Headache ... Kidney disease common ... with Lupus: • Chronic ... #Diagnosis #Rheumatology
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... tightness Most Common ... Nasal polyps and signs ... in the adjacent lung ... , CCP, ANCA • HIV
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
of age • Most common ... (headache and diplopia ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Epidemiology: • Most common ... with no early symptoms ... weeks without infection ... Physical Exam/Signs ... • Neutropenia, anemia
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... vasculitis vs infection ... GCA #Temporal #Signs ... #Symptoms #Diagnosis ... #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... to exclude are infections ... Presentation - Systemic Symptoms ... purpura: strong sign ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... Nodosa: • PAN most commonly ... ischemia • Skin: Erythematous ... Eosinophilia, asthma, chronic ... #Rheumatology
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