21 results
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... T-cell - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... #hematology #Markers ... #Differential #
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis - Differential ... malignancies • Anemia ... inflammatory disorders ... Myelodysplastic syndrome ... Diagnosis #Causes #hematology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Neoplastic / Hematologic ... • Anemia • ... Hepatitis • HIV ... • Somatization Disorder ... Fatigue Syndrome
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Risks factor for HIV ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... Causes #Workup #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic anemia ... • HCV, HBV Not ... #Diagnosis #hematology ... #rheumatology #
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
hypomagnesemia), Eating disorders ... - Diuretics (carbonic ... and lymphomas, IV ... megaloblastic anemia ... #Causes #differential
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... Autoimmunity • Chronic ... autoimmune hemolytic anemia ... , HIV) • Glucocorticoid ... hypogammaglobulinemia #immunology #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... • Symptoms of anemia ... Mycoplasma, EBV, HIV ... younger pts) Differential ... #hematology #diagnosis
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Framework and Management ... Infection - Viral (HIV ... per day until stable ... #Diagnosis #Management
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
2nd pass = Chronic ... NSAIDs/Aspirin, IV ... Eosinophilic GI Disorders ... cell activation syndrome ... #Diagnosis #hematology